I’ve read Combining Client Scripts into a Composite Script and wanted to use it. Then I’ve read Julian Jelfs concerns ScriptManager.CompositeScript issues However the article Combining javascript files with Ajax toolkit library describes workarounds, that make the solution workable. You also can use Script reference profiler: http://aspnet.codeplex.com/releases/view/13356
Using ScriptManager with other frameworks MSDN documentation: CompositeScriptReference The older implementations, that has been superseded by CompositeScript class: ToolkitScriptManager Combining, Compressing, Minifying ASP.NET ScriptResource and HTML Markups